A COMPARATIVE STUDY OF ORAL GLUCOSE CHALLENGE TEST VERSUS SINGLE STEP GLUCOSE TOLERANCE TEST IN ANATENATAL SCREENING FOR GESTATIONAL DIABETES MELLITUS

Author's Name: Dr. M.Sujatha Alagesan & Dr.M.Meena
Subject Area: Health Science
Subject Medicine and Dentistry
Section Research Paper

Keyword:

AN Mothers, GDM, one step, two step tests, efficacy, comparison.


Abstract

Background: Aim: To compare the efficacy of one step and two step tests in detection of GDM during the pregnancy and to confirm the efficacy by diagnostic test. Methodology: The study was conducted in a tertiary level teaching hospital. 348 AN mothers were randomly allotted to each group and screened one group by one step test and another by two step test. The mothers were advised to undergo diagnostic test for confirmation. Results: The two step and one step tests statistically significantly screened 3.2% and 8.0% of GDM mothers respectively (P<0.01). Both groups the GDM mothers significantly positively correlated with their age (r=0.869). Early pregnancies the detection of GDM was not so significant in both groups (P>0.05). In late (third trimester) pregnancies the one step test detected (4.8%) and two step detected (1.5). The detection was significant (P<0.05). Similar observations were made in term deliveries, caesarean deliveries and normal birth weight of babies (P<0.05). GDM mothers were strongly associated with one step test (P<0.01).The odds likelihood + ratio of one and two step tests were 322 times and 35.1 times respectively. Discussions: The one step test predicted positives effectively than the two step test. The effectiveness of the test was reflected in late pregnancies, term and caesarean deliveries and normal birth weight of babies. The positive predictions of one step test was significantly 287 times more than that of two time test. Conclusion: By considering simplicity and one time effective application and prediction the one step test may be advocated to the expectant mothers.

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