IMPACT OF MALARIA AND HIV CO-INFECTION ON THE HEMATOLOGICAL AND IMMUNOLOGICAL PARAMETERS OF HIV-POSITIVE WOMEN IN ABIDJAN (Ivory Coast)

Author's Name: KAMAGATE Soualio, KOKORE Angoua Baudouin, BLEYERE Nahounou Mathieu & Paul Angoué YAPO
Subject Area: Health Science
Subject Other
Section Research Paper

Keyword:

Co-infection; malaria ; HIV; hematological and immunological parameters; Abidjan, Côte d’Ivoire).


Abstract

Our study aimed to study the behavior of hematological and immunological parameters in women co-infected with malaria and HIV / AIDS. This was a comparative study over a period of one (1) year from January 2017 to December 2018. It was conducted in the Integrated Center for Bioclinical Research Abidjan (CIRBA). This study included 75 non-malarial HIV-positive women and 50 HIV-positive women with malaria.The results indicated that erythrocyte level, anemia was very common in 70% of HIV-positive women compared to 57,3% in HIV-positive non-malarial women. Thrombocytosis was only present in HIV-infected women with 40% malaria. The prevalence of neutropenia was observed in 68% of HIV-infected women with malaria compared with 40% of women with non-malarial HIV. Eosinophilia was reported in 36% of HIV-positive women compared with 17,3% of women in non-malarial seropositive women. As for lymphopenia, it was revealed in 22% of HIV-positive women compared to 2,7% of women with non-malarial HIV. According to CD4 levels, a high prevalence of immunodeficiency was observed in 36% of HIV-positive women compared to 10,7% of women in non-malarial seropositive women.This study shows that co-infection with HIV / AIDS has led to a very significant decrease in certain haematological and immunological parameters in co-infected women.

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