PREVALENCE OF VAGINAL CANDIDA COLONIZATION AMONG WOMEN ATTENDING UNIVERSITY OF NIGERIA TEACHING HOSPITAL, ENUGU STATE, NIGERIA.

Author's Name: Joachim O. Ezeadila, Christie A. Oyeka, Ikechukwu Okoli & Lilian C. Chidi-Onuorah
Subject Area: Life Sciences
Subject Malacology
Section Research Paper

Keyword:

Prevalence, Candida species, vaginal colonization, Enugu State.


Abstract

Candida species live in a healthy vagina as normal flora and about 75% of women generally harbour these yeasts which sometimes can become pathogenic causing vaginal candidiasis. This study was undertaken to determine the prevalence of vaginal Candida colonization among women attending the Obstetrics and Gynecology Unit of the University of Nigeria Teaching Hospital, Ituku/Ozalla, Enugu State, Nigeria. A total of 340 high vaginal swab (HVS) specimens were collected from the women and cultured on Sabouraud Dextrose Agar supplemented with Chloramphenicol (50µg/ml.) and incubated at 25°C for 24 hours. Identification was done using standard methods which included growth on Chromogenic Candida agar. Statistical analysis was done using Chi-square test (p<0.05). Eighty-eight (88) Candida species were isolated with Candida tropicalis (34) being the most predominant (38.63%) followed by Candida parapsilosis 21 (23.86%), Candida albicans 20 (22.73), Candida krusei 7 (7.95%) and Candida glabrata 6 (6.82%). Women ?50 years had the highest prevalence of Candida colonization (50%) followed by the age group 18 – 25 years (29.6%), though the difference was not statistically significant (p = 0.067). The prevalence was higher amongst the non-pregnant women (28.6%) than the pregnant women (16.0%), while women in their first trimester had the highest prevalence of 25.0% followed by those in the second trimester (11.1%) and third trimester (5.0%). Symptomatic and asymptomatic women had a prevalence of 23.3% and 29.2% respectively. This study recommends that vaginal candidiasis should not be ruled out if there are no symptoms and thus, proper diagnosis be carried out especially in pregnant women notwithstanding the absence of symptoms in order to avoid complications.

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